Cardiovascular diseases (CVDs) encompass a broad range of disorders that impair the function of the heart and blood vessels. CVDs remain as primary cause of death and disability globally. These conditions are influenced by complex factors including lipid metabolism dysfunction, hypertension, oxidative stress, inflammation, and genetic susceptibility. To facilitate the study of cardiovascular pathophysiology and accelerate therapeutic discovery, our platform offers a comprehensive portfolio of in vivo cardiovascular disease models.

These models replicate key human disease phenotypes such as hyperlipidemia, atherosclerosis, thrombosis, myocardial infarction, heart failure, and hypertensive cardiomyopathy. They are established using genetic modifications, surgical interventions, or pharmacological induction to closely mimic clinical scenarios.