Spontaneous tumor models are invaluable tools in cancer research, as they closely mimic the natural development and progression of human cancers. Unlike transplanted tumor models, spontaneous tumor models arise from genetic alterations within the organism, providing insights into tumor initiation, progression, and metastasis in an immunocompetent environment. These models are particularly useful for studying the complex interactions between tumors and the immune system, as well as for evaluating the efficacy of anticancer therapies in a setting that closely resembles human physiology.

We have a collection of spontaneous tumor mouse models targeting four major cancer types frequently observed in humans: pancreatic cancer, hepatobiliary cancer, breast cancer, and colorectal carcinoma.